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The ambiguous value of cognitive behavioral therapy to antidepressants in children and adolescents suffering from Major Depressive Disorder an umbrella-review

Groot, Annick de (2023) The ambiguous value of cognitive behavioral therapy to antidepressants in children and adolescents suffering from Major Depressive Disorder an umbrella-review. Bachelor thesis, Psychology.

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Abstract

Depression in children and adolescents is common, across cultures all over the globe. However, this field is still understudied. Despite the major consequences. Combination therapy, mainly Fluoxetine and cognitive behavioral therapy, is recommended nowadays in children and adolescents suffering from moderate to severe depression. However, little is known about the efficacy of combination therapy and the unique added value of cognitive behavioral therapy to antidepressants. This umbrella review searched systematically for systematic reviews in PubMed and PsycINFO, and included 7 systematic reviews and 13 RCTs. According to the results, cognitive behavioral therapy seems to have a positive significant added value for Bupropion, in terms of Efficacy, and Fluoxetine, in terms of Efficacy and immediately post-intervention Remission. However, follow-up studies for Fluoxetine plus cognitive behavioral therapy on Remission favor the control condition: Fluoxetine monotherapy. So, it is still not clear whether cognitive behavioral therapy has a positive or negative added value to most of the included antidepressants. Because, the added value depends upon each pharmacological intervention, and is, therefore, still rather ambiguous. Thus, more research should be conducted on this. Further research should also be focused upon generating more RCTs in this particular field. Because, despite the urgence and need for more insights, this field is still understudied. Keywords: major depressive disorder, combination therapy, cognitive behavioral therapy, antidepressants, children, adolescents

Item Type: Thesis (Bachelor)
Supervisor name: Roest, A.M. and Eisma, M.C.
Degree programme: Psychology
Differentiation route: None [Bachelor Psychology]
Date Deposited: 10 May 2023 07:14
Last Modified: 10 May 2023 07:14
URI: http://gmwpublic.studenttheses.ub.rug.nl/id/eprint/1950

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