Ruhig, Ruth (2023) Mastocytosis: Determinant. Master thesis, Psychology.
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Abstract
Keywords: Mastocytosis, Cognitive Complaints, Emotional Distress, Fatigue, Coping Cognitive complaints are reported to co-occur with Mastocytosis, a disease characterized by clonal proliferation of abnormal mast cells. Whether these cognitive complaints can be linked to the disease directly or may rather be attributed to psychological factors (emotional distress, fatigue and coping) is currently unknown. This study investigated neuropsychological symptoms in mastocytosis, using self-report data and physiological markers, to gain more insight in possible associations with, and predictors of, cognitive complaints, mental and physical fatigue in Mastocytosis. The sample consisted of 234 subjects with Mastocytosis, consulted via the University Medical Centre Groningen. Significant predictors of cognitive complaints were depression, fatigue and passive coping. Symptoms and sBT could not predict cognitive complaints in mastocytosis. Variation in mental and physical fatigue was accounted for by mastocytosis symptoms, depression and avoidant coping. Findings indicate that depression, mental fatigue and passive coping may play a particularly crucial role in subjective cognitive functioning. Fatigue in mastocytosis may be a symptom of depression as well as a consequence of mast cell burden directly.
| Item Type: | Thesis (Master) |
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| Supervisor name: | xx, xx |
| Degree programme: | Psychology |
| Differentiation route: | Clinical Neuropsychology (CN) [Master Psychology] |
| Date Deposited: | 08 Aug 2023 07:27 |
| Last Modified: | 19 Apr 2024 14:10 |
| URI: | http://gmwpublic.studenttheses.ub.rug.nl/id/eprint/2733 |
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