Lell, Alexander (2023) Predictors of relapse after CBT for anxiety disorders in children and adolescents: An Individual Patient Data Meta-analysis. Master thesis, Psychology.
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Abstract
While cognitive behavior therapy (CBT) is the first-line treatment recommendation for anxiety disorders in children and young people (CYP) in international treatment guidelines, relapse rates remain high and involved factors are poorly understood. The present work aimed to increase understanding by means of an individual patient data meta-analysis (IPDMA) with the primary aim of investigating whether treatment dose, disorder type and/or an interaction thereof can predict relapse rates. To this end, we systematically searched the COCHRANE database, Medline, PsycINFO, Eric, and CINAHL for randomized controlled trials (RCTs) examining CBT for anxiety disorders in CYP, in which diagnostic assessments were conducted at pre-treatment, post-treatment and at a follow-up. Individual patient data was provided by the authors of 47 out of 115 eligible RCTs. Of the data received, 19 RCTs had been synthesized at the time of writing with 663 participants from 14 RCTs contributing to the analyses. Across included RCTs, 20.1% of participants suffered relapse of any anxiety disorder. Relapse rates were the same for social anxiety disorder and for specific phobias (18.2% vs. 18.7%, respectively) but this difference was not statistically significant. Nor did treatment dose or the interaction between treatment dose and disorder type predict relapse rates. The present work found fairly similar relapse rates compared to previous work in the field. The hypothesized moderation was not found. However, statistical power was limited. Results could, therefore, be a consequence of lacking power rather than no effect. Identifying reliable predictors of relapse may ultimately pave the way for tailored approaches to relapse prevention.
| Item Type: | Thesis (Master) |
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| Supervisor name: | Kooiman, B.E.A.M. and Nauta, M.H. |
| Degree programme: | Psychology |
| Differentiation route: | Clinical Psychology (CP) [Master Psychology] |
| Date Deposited: | 01 Sep 2023 09:44 |
| Last Modified: | 01 Sep 2023 09:44 |
| URI: | http://gmwpublic.studenttheses.ub.rug.nl/id/eprint/2851 |
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