Koning, Yaël (2025) Sex differences in the incidence rate of affective psychotic disorder. Master thesis, Psychology.
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Abstract
Psychotic disorders, often characterized by hallucinations and/ or delusions, can lead to significant health risks for patients. They result in higher suicide rates, decreased life expectancy and higher rates of premature death. Incidence rates can vary between samples and populations, and may also differ between sexes, making it difficult to estimate a valid incidence rate. Previous research has focused on an overall incidence rate for all psychotic disorders. For this research, the focus is on the incidence rates for men and women in affective psychotic disorders and the possible differences. Historically, women were often left out of clinical trials. Now that women are participating, it is important to see if differences between men and women exist. If they do exist, this could potentially contribute to better health care for women and men. It is hypothesized that the incidence rate for affective psychotic disorder is higher in women than men. To test this hypothesis, a meta-analysis was performed. The inclusion criteria were 1) all affective psychotic disorders and 2) incidence rates for men and women. After title screening, abstract screening, full text screening and data extraction, eight studies met the inclusion criteria. After computing the incidence rate ratio, it was found that women are diagnosed more often than men with an affective psychotic disorder (IRR = 0.5326, P < 0.0001). The pooled incidence rate for men was 12,6 per 100.000 person-years, for women this was 23,8 per 100.000 person-years. It is recommended to invest in more research on female populations, to see if there are different risk factors for women than men, if women might need different treatment than men, and whether or not we as a society can contribute to better outcomes by early recognition of an affective psychotic disorder.
| Item Type: | Thesis (Master) |
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| Supervisor name: | Eisma, M.C. |
| Degree programme: | Psychology |
| Differentiation route: | Clinical Psychology (CP) [Master Psychology] |
| Date Deposited: | 04 Mar 2025 13:22 |
| Last Modified: | 04 Mar 2025 13:22 |
| URI: | http://gmwpublic.studenttheses.ub.rug.nl/id/eprint/4745 |
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